Adrenal failure. Yukina M.Yu., Nuralieva N.F., Troshina E.A.

The book considers etiology and the features of the pathogenesis of adrenal failure are clarified: genetic predictors of the development of pathology are described in detail, modern ideas about the mechanisms of immune tolerance in the autoimmune form of the disease are reflected. Actual issues of the chronology of the development of clinical manifestations and laboratory changes in hypocorticism are affected. Diagnostic approaches, as well as features of differential diagnosis of the disease, are described. Given the latest international recommendations, the tactics of patients are presented. In particular, the features of the replacement therapy of adrenal failure are examined in detail, a detailed algorithm for the provision of medical care with addison crisis is given. The need for a regular examination of this cohort of patients is emphasized. Various methods of forecasting the development of adrenal failure for its timely diagnosis are also discussed, new therapeutic targets are considered.

for general practitioners, endocrinologists, as well as senior students of medical universities.