Hypercoagulation. Pogorelov V.M., Urtaev B.M., Simanin R.A., Protsenko D.D.

It is known that the disease can manifest itself by an excessive adaptive response of the body to some factors of the internal or external environment. The decisive role in the mechanisms of human adaptation is often played by the functional state of the blood system. The book discusses in detail the hemostatic activity of blood with acute blood loss and bacterial or viral sepsis. A comparison of these two polar coagulopathy shows that red blood cells and platelets, under normal conditions, interacting and complementing each other, protect the body with an increase in blood coagulation - hypercoagulation. This adaptive response of the body to damage to tissues and organs is characterized by deadly pathological redundancy, in one case leading to bleeding, in the other to thrombosis and thromboembolism. Along with the issues of pathogenesis of hypercoagulation, the book discusses the basic functions of the blood, as well as methods of correction of hemostasis and individual issues of the history of transfusiology.

For anesthesiologists-resuscitators, transfusiologists, infectious disease specialists.