Miastenia and myasthenic syndromes. 3rd edition, processed and supplemented. Sananze A.G.

This manual covers modern ideas about epidemiology, pathogenetic mechanisms for the formation of motor disorders, clinical forms, diagnostic criteria, as well as strategies and tactics of treatment of myasthenia and myasthenic syndromes. The third edition of the book additionally emphasizes the relevance of the problem, determined by the undoubted increase in the frequency of occurrence and objective difficulties in diagnosing myasthenia, as well as the indisputable interest of doctors of various specialties in the presented information.

Features of the distribution of motor disorders and their relationship with the age of the debut of the disease, the factor of the presence or absence of Timoma, the absence of the dependence of the severity of the disease on the concentration of autoantibodies to acetylcholine receptors and other synaptic and extrainaptic antigenic targets show the inhomogency of the group of patients united by the diagnosis "Miastenia." В связи с этим представленные методы количественной оценки выраженности двигательных расстройств (QMGs), а также современная клиническая классификация (MGFA) в сочетании с иммунологическими исследованиями концентрации аутоантител к ацетилхолиновым рецепторам, титин-белку, потенциалзависимым кальциевым каналам наряду с традиционными фармакологическими пробами и электромиографическим тестированием нервно -MATO transmission are criteria for diagnosis of myasthenia.

The publication is intended for doctors of various medical specialties.