NGS. High -performance sequencing. 5th edition. Rebrikov D.V., Korostin D.O., Shubina E.S.

Various options and features of modern methods for determining the structure of nucleic acids (methods of sequencing of the second and third generations) are considered. The principles of the most popular high -performance sequencing technologies (NGS) are described. The classification of high -performance sequencing methods in several parameters is given. The main elements of the primary analysis of large -scale sequencing data are given. Separate chapters are devoted to the use of NGS to solve various biological problems: sequencing of prokaryotic and eukaryotic genomes and transcription, metagenomic sequencing, as well as the use of NGS in medical practice.

for employees of genetically engineering and medical diagnostic laboratories, as well as for teachers and students specializing in the field of molecular biology and biotechnology.